Enantiopure ethyl 2,3‐dibromopropionate: Enantioselective synthesis vs preparative HPLC enantioseparation of racemate on multigram scale
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چکیده
منابع مشابه
Enzyme-catalysed regio- and enantioselective preparative scale synthesis of (S)-2-hydroxy alkanones
a-Hydroxy alkanones were synthesised with high enantiomeric purity by stereoselective enzyme-catalysed diketone reduction. Both diketone reduction and cofactor regeneration were accomplished with purified carbonyl reductase from Candida parapsilosis (CPCR2). The reaction products were isolated by column chromatography and analysed by chiral GC measurements, H-NMR spectroscopy and determination ...
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ژورنال
عنوان ژورنال: Chirality
سال: 2020
ISSN: 0899-0042,1520-636X
DOI: 10.1002/chir.23260